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KMID : 1004820090100020045
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Journal of Biomedical Research
2009 Volume.10 No. 2 p.45 ~ p.52
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Flavonoids and their free radical reactions
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Han Jin-Yi
Hong Jin-Tae
Nam Sang-Yoon
Oh Ki-Wan
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Abstract
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Flavonoids are a large family of polyphenolic compounds synthesized by plants that have acommon chemical structure. Flavonoids may be further divided into subclasses, Anthocyanidins, Flavan-3-ols, Flavanones, Flavonols, Flavones, Isoflavones. Flavonoids have antioxidant and antiradical activities. Theantiradical efficacy of flavonoids have established structure-activity relationships (SAR) of the antioxidantactivity. Reactivity of flavonoids is highly dependent on the configuration of OH groups on the flavonoid Band C rings, there being little contribution from A ring to antioxidant effectiveness. This short article presentsthe current knowledge on structural aspects on their free radical reactions of flavonoids.
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KEYWORD
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Flavonoids, Free radical, Antioxidant, TEAC, SAR
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